Physician-formulated eye nutrition

The science of sight,
delivered as daily nutrition.

Physician-formulated daily supplements, made with clinically-studied ingredients at transparent, fully-labeled doses — crafted by eye specialists and third-party tested for purity.

Physician-formulated eye supplements
Macutene Protect Neuroptene Perfect Pressure
The formulas

Each formula supports a different part of your vision

Macutene Protect supports the macula and retina.* Neuroptene supports healthy eye pressure already within the normal range and healthy ocular blood flow.*

Macutene Protect
Macula & retina

Macutene® Protect

Customer reviews on Amazon

Developed by retina specialists — a Certified AREDS2-based formula with more than twice the lutein & zeaxanthin for optimal macular support.

From $33.99/mo Shop Macutene
Neuroptene
Healthy pressure already within the normal range*

Neuroptene® Perfect Pressure

Customer reviews on Amazon

Developed by eye specialists to support healthy eye pressure already within the normal range, ocular blood flow, and the optic nerve.*

From $29.74/mo Shop Neuroptene
The complete routine · Best value
Get both formulas & save 20%
Head-to-retina support, delivered monthly. Cancel anytime.
$59.98/mo
$74.98
Build my routine
Why Pristene

Most people don't get enough nutrition to protect their eyes through diet alone.

Pristene was founded by physicians who saw it every day — patients wanting to protect their vision, looking for clear information about the supplements they take. So we built the products we wished existed: grounded in clinical research, dosed at meaningful levels, and transparent to the last milligram.

Macutene®Macula & retina
Lutein & Zeaxanthin
Macular carotenoids
25+5 mg
Vitamin C
Antioxidant vitamin
500 mg
Zinc
Essential mineral
25 mg
Bilberry
Anthocyanin botanical
30 mg
Copper
Trace mineral
1 mg
Quercetin
Plant flavonoid
14 mg
Neuroptene®Pressure & optic nerve
Niacinamide (B3)
Vitamin B3
250 mg
Bilberry
Anthocyanin botanical
160 mg
Grape Seed
Polyphenol extract
100 mg
CoQ10
Cellular antioxidant
50 mg
Saffron
Botanical extract
30 mg
Proanthocyanidins
Flavonoid complex
95 mg
Trusted by professionals

Recommended by eye-care specialists

Leading ophthalmologists and optometrists on why they reach for Pristene.

Most patients aren't getting enough nutrition to support their eyes through diet alone, so I recommend Pristene supplements to provide the nutrition they need for healthy eyes.

PK
Peter Kaiser, MD
Professor of Ophthalmology · Cole Eye Institute, Cleveland Clinic

As an optometrist, it's important to me to recommend the best eye supplements to my patients — that's why I choose Pristene.

PK
Paul Karpecki, OD
Clinical Director, Corneal Services & Advanced Ocular Surface Disease · Kentucky Eye Institute

As an ophthalmologist, it's important to me to recommend the best eye supplements to my patients — that's why I choose Pristene.

RV
Rohit Varma, MD
Board-Certified Ophthalmologist · Founding Director, Southern California Eye Institute
Our community

Real people. Real results.

Deb · Verified customer
Verified buyers on Amazon

Macutene® Protect

All Macutene reviews →
★★★★★

"My 85-year-old mother asked me to order these — she'd heard so many good things. She asked for two more bottles. Mom knows best!"

Sue · CT ✓ Verified buyer
★★★★★

"I've been taking this product for over a year and have found it very beneficial for my eyes. I will definitely continue buying it."

Mac ✓ Verified buyer
★★★★★

"Really pleased with my purchase — excellent for the care and health of the eyes. Thank you!"

Rebeca S. ✓ Verified buyer

Neuroptene® Perfect Pressure

All Neuroptene reviews →
★★★★★

"So tired of buying supplements that hide behind proprietary blends. Neuroptene actually lists everything clearly, and the dosages are legit. Will definitely be repurchasing."

Ana Campos ✓ Verified buyer
★★★★★

"Now that I'm 50, it's important to me to take my health seriously and that includes my eyes. Two capsules per day taken consistently — quite pleasant, which makes it easy to take. I'm sticking with it!"

hiding.in.the.pages ✓ Verified buyer
★★★★☆

"A little pricey. But I think they work quite well."

Kai4Kai ✓ Verified buyer
How it works

A simple daily routine, grounded in the science

01
Daily habit

Two capsules a day

An easy habit — take it with your morning routine, any day of the week.

02
Real doses

Clinically-studied levels

Nutrients delivered at the doses used in research — not the minimums that fit a label.

03
Over time

Long-term support

Consistent daily nutrition to support the macula, retina, and optic nerve.*

Our promise

Try it for 60 days, risk-free

If Pristene isn't right for you, email us within 60 days for a full refund — no questions asked. Free shipping on every subscription.

Start today
Physician Formulated
Lab-Tested
cGMP
Non-GMO
Gluten-Free
Vegan
Physician-FormulatedAREDS2®-BasedcGMP FacilitiesThird-Party Tested