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  •  A Better Nature-Based AREDS2 Formula with More Lutein & Zeaxanthin and Additional Clinically Proven Ingredients for Optimal Macular Health. 

Developed by retina specialists, Macutene® Protect is a Certified AREDS2-based formula that contains or exceeds all the ingredients used in the AREDS2 clinical trial and has more than twice the amount of lutein & zeaxanthin to provide optimal macular support.

  • Macutene® Protect Benefits:
  1. Help Preserve sharp, detailed vision*
  2. Help Strengthen Night Vision*
  3. Help Reduce Eye Strain*
  4. Contains Additional Ingredients Clinically Proven to Support Optimal Macular Health
  • Macutene® Protect Ingredients:

Macutene® Protect contains lutein, zeaxanthin, meso-zeaxanthin (as part of zeaxanthin), zinc, copper, vitamins C & E, bilberry, green tea and quercetin at optimal levels for macular health. Learn More about our ingredients here.

  • Certified to the Highest Standards
  1. NSF Certified - Macutene® Protect is certified by the NSF (the world's leading organization for dietary supplement testing) and is tested for NSF/ANSI 173, the only American National Standard for testing and certifying dietary supplements.  NSF has independently tested Macutene® Protect to verify the supplement facts panel and test for the presence of toxins and/or contaminants.
  2. Certified Vegan - Macutene® Protect has no animal products or byproducts and that have not been tested on animals. 
  3. Certified Gluten-Free - Macutene® Protect is Certified Gluten-Free by the Gluten Intolerance Group representing unmatched reliability for meeting the strictest of gluten-free standards.
  4. Non-GMO - Macutene® Protect contains is produced without genetic engineering and does not contain any genetically modified organisms (GMOs).
  5. Manufactured in the United States with local and globally sourced ingredients.
  6. Dye-free, egg-free, dairy-free with no artificial colors or preservatives. 

Macutene® Protect is manufactured in a cGMP certified facility in the United States with local and globally sourced ingredients.


    We recommend consistent use every month for optimal eye support.
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    Carefully formulated from natural ingredients

    Macutene® Protect contains 8 different nature-based ingredients that are specifically shown to help support eye health.

    • Brand

      Lutein & Zeaxanthin

      Powerful nutrients that block photo-oxidative damage to the retina from high-energy light waves. These carotenoids are only available through diet and work to protect eyes from inflammation.

      Found in: Kale, spinach, broccoli

    • Brand

      Potent Antioxidants

      Antioxidants such as Bilberry, Quercetin and EGCG contain potyphrnals that help reduce dryness and other signs of eye fatigue from screen time.

      Found in: Bilberry fruit, green tea, blueberries, onions, tomatoes

    • Brand

      Vitamin C

      Helps form collagen, a protein that provides structure to eyes.

      Found in: Citrus and tropical fruits, bell peppers

    Green Tea
    Lutein & Zeaxanthin

    The lutein and zeaxanthin in Macutene® Protect is sourced from naturally derived marigold extract from Non-GMO marigold seeds.


    A superfood containing anthocyanidins, a powerful antioxidant that helps protect the retina and support night vision.

    Vitamin C

    A powerful antioxidant. The Vitamin C in Macutene® Protect is the purest form of vitamin C approved by the Vitamin C Foundation.

    EGCG Antioxidants

    A powerful antioxidant found in green tea, EGCG supports macular health by protecting from free radicals.

    Vitamin E

    Protects cell membranes against oxidation from free radicals and supports retinal health.


    The retina contains high amounts of zinc and the evidence suggests that sufficient levels support macular health and normal dark adaptation.


    Encourages the development of flexible connective tissue for proper eye structure and helps supplement the intake of zinc.


    Found in fruits and vegetables, quercetin is a potent antioxidant that helps support retinal health.


    Macutene® Protect and the AREDS2 Clinical Trial

    The Age-Related Eye Disease Study (AREDS®) and the AREDS2® clinical trials were led by the National Eye Institute (part of the U.S. National Institutes of Health). The AREDS® and AREDS2® clinical trials determined that daily high doses of antioxidants and minerals can help support macular health.

    Macutene® Protect is an AREDS2® based formulation of ultra-premium ingredients to support macular health.

    View Supplement Label

    Endorsed by ophthalmologists

    • We’re serious about facts. Ask away

      What is Macutene Protect?

      Macutene® Protect is a nature-based dietary supplement designed to specifically support the macula and retina. It contains all of the ingredients used in the AREDS2 clinical trial and also has additional lutein, zeaxanthin, meso-zeaxanthin, bilberry, green tea, and quercetin at optimal levels for macular and retinal health. Macutene Protect is a certified vegan, certified gluten-free, and non-GMO supplement that has been certified by the NSF to ensure quality, purity, and potency of ingredients.

      What is Macutene Protect's return policy?

      While we hope you love Macutene® Protect, if it isn’t the right fit for you, we offer a 60-day no questions asked return policy. Just e-mail us at, and we will take care of you!

      Who can benefit from using Macutene Protect?

      Macutene Protect can benefit people looking to support their macular and retinal health and optimal eye health with its carefully formulated blend of carotenoids (lutein, zeaxanthin), vitamins, minerals, and antioxidants like bilberry and quercetin.

      How long does it take to start seeing the benefits of Macutene Protect?

      Macutene Protect is intended to SUPPORT your eyes. It does not treat or cure any eye disease or condition. Instead, it is meant to help supplement your diet with the carotenoids and other nutrients that your eyes need for optimal health.

      How should I take Macutene Protect? Is there a recommended dosage?

      Macutene Protect should be taken as 2 capsules per day. Either both capsules at once or 1 capsule twice daily.

      Can I take Macutene Protect together with other supplements or medications? Are there known side effects associated with using Macutene Protect?

      There are no known side effects of taking Macutene Protect as it is a nature-based supplement. Please contact your primary care physician before starting Macutene Protect or any new dietary supplement to ensure that it will not affect or interfere in any way with your well-being.

      Have another question for us?

      We love hearing from our customers! You can e-mail us at or click here for our contact form and we will be in touch!

    • Have questions?

      Chat with our customer support team.
Monday - Friday 9am to 6pm (EST).

      You can also text or call us at:1-855-622-8836

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