Neuroptene bottle
Eye Pressure and Blood Flow

Neuroptene®
Perfect Pressure

★★★★☆4.4 · 1,250+ Amazon ratings

Neuroptene® Perfect Pressure is a dietary supplement developed by eye specialists to support healthy eye pressure and optic nerve health. It contains nature-based ingredients studied for their role in supporting healthy ocular circulation, neutralizing free radicals, and nourishing the optic nerve.*

Supports healthy eye pressure already within the normal range*
Rich in antioxidants to combat free radicals
Nourishes the optic nerve*
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One-time purchase30-day supply · 60 capsules $34.99
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What it does

Daily support for eye pressure & blood flow

Neuroptene® focuses on a different part of healthy vision than the macula — the pressure inside the eye and the blood flow that feeds the optic nerve.

High-dose niacinamide

250 mg of vitamin B3 — studied for its role in the health and resilience of the optic nerve.

Circulation antioxidants

Bilberry, grape seed and CoQ10 support microcirculation and healthy ocular blood flow.

For the long run

Two capsules a day, dosed to the levels used in research.

The formula

Six actives for the pressure behind healthy vision

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250 mg

Niacinamide (B3)

A high dose of vitamin B3, studied for its role in supporting the health and resilience of the optic nerve.

160 mg

Bilberry

Anthocyanin-rich fruit extract that supports microcirculation and helps protect the retina and night vision.

100 mg

Grape Seed

A source of proanthocyanidins — potent antioxidants that support healthy blood flow behind the eye.

50 mg

CoQ10

Fuels cellular energy production and helps protect ocular tissue from oxidative stress.

30 mg

Saffron

A carotenoid-rich extract studied for supporting retinal cells and comfortable vision in low light.

95 mg

Proanthocyanidins

Standardized from grape seed — the antioxidant backbone that supports vascular health around the eye.

The science

Support for eye pressure & ocular blood flow

Healthy vision depends on more than the macula. Neuroptene® targets the pressure inside the eye and the blood flow that nourishes the optic nerve — combining high-dose niacinamide with antioxidants that support microcirculation.

Every ingredient is dosed at a meaningful level and listed transparently on the label. No proprietary blends, nothing hidden.

2
Capsules daily
30
Day supply
6
Active ingredients
Physician Formulated
Lab-Tested
cGMP
Non-GMO
Gluten-Free
Vegan
Supplement Facts
Serving Size 2 Capsules
Servings Per Container 30
Amount Per Serving% DV
Niacinamide (Vitamin B3)250 mg NE1,563%
Bilberry (Vaccinium myrtillus) Fruit Ext.160 mg
Grape Seed (Vitis vinifera) Extract100 mg
Proanthocyanidins (from grape seed)95 mg
Coenzyme Q10 (ubiquinone)50 mg
Saffron (Crocus sativus) Stigma Extract30 mg
† Daily Value (DV) not established. NE = niacin equivalents.
Other ingredients: microcrystalline cellulose, hydroxypropyl methylcellulose, magnesium stearate, delayed-release vegetable capsule.
Non-GMOCertified VeganGluten-Free
What to expect · Daily use

Benefits that build over time.

Niacinamide, CoQ10, saffron and bilberry deliver daily support and long-term nutritional coverage with consistent use.*

Week 1Daily nutrient intake begins supporting ocular blood flow and cellular energy.
Week 4Niacinamide and CoQ10 levels build to provide ongoing mitochondrial support to the optic nerve.
Week 8+Sustained nutrient levels help maintain long-term optic-nerve nutrition and daily ocular support.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Why the dose matters

Most B-complex supplements stop at 50 mg

Emerging research on optic-nerve support points to meaningfully higher levels of niacinamide. Neuroptene is built around that dose.

250mg
Niacinamide in Neuroptene®
50mg
Typical B-complex pill
Why it's different

Made to a higher standard

Targets: Eye Pressure and Blood Flow — a daily formula built on clinical research, dosed transparently, and tested for purity.

Physician-formulated
Created by practicing ophthalmologists.
Clinically-studied doses
Dosed to the levels used in research.
Transparent, full-dose label
Every ingredient and milligram, printed.
Third-party tested
Independently verified for purity & potency.
Vegan, gluten-free & non-GMO
Clean, nature-based capsules.
Made in cGMP facilities
Produced in U.S. cGMP-certified facilities.
Built for real life

Support your vision when the light gets low.

From morning trails to evening drives — saffron and bilberry help support comfortable vision in changing light.

Try Neuroptene
Reviews

Rated 4.4 by 1,250+ Amazon customers

★★★★☆4.4 · 1,250+ verified Amazon ratings
★★★★★

"So tired of buying supplements that hide behind proprietary blends. Neuroptene actually lists everything clearly, and the dosages are legit. I appreciate that they included saffron — not many brands do. Will definitely be repurchasing."

Ana Campos ✓ Verified buyer
★★★★★

"Now that I'm 50, it's important to me to take my health seriously and that includes my eyes. Two capsules per day taken consistently — the smell and taste are actually quite pleasant, which makes it easy to take. I'm sticking with it!"

hiding.in.the.pages ✓ Verified buyer
★★★★★

"This is great for my eyes! I'm often reading — books or on the computer — and it can cause my eyes to feel strained. The supplement is easy to swallow and doesn't upset my stomach."

Gwen ✓ Verified buyer
★★★★★

"Using this as part of a broader health routine. Can't isolate the impact, but I trust this brand."

Zhanar T. ✓ Verified buyer
★★★★★

"First order from the company. I like the fact that it's a capsule and not a hard pill, and there is no aftertaste."

I Bas ✓ Verified buyer
★★★★☆

"A little pricey. But I think they work quite well."

Kai4Kai ✓ Verified buyer
FAQ

Questions, answered

What is Neuroptene® Perfect Pressure? +
A nature-based dietary supplement formulated to support healthy eye pressure, ocular blood flow, and the optic nerve. It pairs a high 250 mg dose of niacinamide with bilberry, grape seed, CoQ10 and saffron.
How is it different from Macutene® Protect? +
Macutene supports the macula and retina (an AREDS2-based formula). Neuroptene targets eye pressure and the blood flow behind the optic nerve. Many customers take both — that's our Shop the Routine bundle.
How should I take it? +
Two capsules per day, with or without food.
Can I take it with Macutene? +
Yes — the two formulas are designed to complement each other and can be taken the same day. Consult your physician before starting any new supplement.
What's your return policy? +
A 60-day, no-questions-asked return policy. Email support@pristene.com and we'll take care of you.

Protect the pressure behind your vision

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Held to a higher standard

Physician-FormulatedAREDS2®-BasedcGMP FacilitiesThird-Party Tested1,250+ Amazon Ratings