pristene®
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Our science

Formulated by physicians. Grounded in research.

Every Pristene formula starts with clinical evidence — not trends — and is dosed to the levels used in the research.

AREDS2®-based · Physician-formulated · Third-party tested · cGMP
Macular science · AREDS2®
Clinical foundation

Built on landmark trials

The Age-Related Eye Disease Studies (AREDS and AREDS2) were multi-year clinical trials led by the U.S. National Eye Institute. AREDS2 refined the original formula — adding lutein and zeaxanthin — and helped define the antioxidants and minerals that support macular health.

Most supplements fall short of those researched doses. Macutene® Protect is built to them — then enriched with bilberry, green tea and quercetin, transparent to the last milligram.

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Full transparency

Dosed to the research, not the label

The exact actives and amounts across our two formulas — Latin names, milligrams, nothing hidden.

Lutein & Zeaxanthin
Tagetes erecta
25 + 5 mg Macutene®
Vitamin C
Ascorbic acid
500 mg Macutene®
Zinc
Zinc citrate
25 mg Macutene®
Bilberry
Vaccinium myrtillus
160 mg Neuroptene®
Saffron
Crocus sativus
30 mg Neuroptene®
Our philosophy

Where nature meets the lab

Nature already makes many of the nutrients your eyes rely on* — the gold of marigold lutein, the violet of bilberry, the crimson of saffron. Our work is to treat those botanicals with scientific discipline. Three principles guide every formula:

Evidence firstMarigold, bilberry & saffron — nutrients and botanicals chosen for peer-reviewed research, not trends.
Doses that matterFormulated to the levels used in research — then third-party tested for purity and potency, every batch.
Science you can readA label like a study — Latin names, exact milligrams, nothing hidden.
Quality, verified

Held to a higher standard

Physician Formulated
Lab-Tested
cGMP
Non-GMO
Gluten-Free
Vegan
Endorsed by ophthalmologists

"Most patients aren't getting enough nutrition to support their eyes through diet alone, so I recommend Pristene® supplements."

Peter Kaiser, MD · Cole Eye Institute, Cleveland Clinic · Pristene Medical Advisory Board & Investor

Science you can take daily

Explore the formulas built on it.

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